News of Chemical Informatics

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News of Chemical Informatics

 

Chemical Informatics is Insight medical publisher  journal and also one of the most emerging fields in the present scenario. It is a multidisciplinary field which covers the research containing molecular design tools for finding the best fitting compounds which address to particular targets.

Chemical Informatics is a vast field that aims to disseminate information regarding the design, structures, creation, dissemination, visualization and the use of chemical information. Chemical Informatics Journal aims to supply scientists of resources in order to provide the scientific knowledge through the publication of peer-reviewed, high quality, scientific papers and other material on all topics related to Chemical information, Software and databases.

BPA's counterpart replacement BPS can hinder heart function

The study is the first to show the instant effects bisphenol S (BPS) can have on the heart.

"We expected to find similar effects from BPS as we have with BPA, but not at the speed that it worked," said biomedical sciences professor Glen Pyle, who conducted the study with former master's student Melissa Ferguson. "This replacement chemical seems to be more potent."

Bisphenol A (BPA), a chemical used in plastic products, was banned from baby bottles in Canada in 2010 over concerns that it may leach into foods and cause hormone-related side effects. More manufacturers are now using BPS as a replacement in their products and labelling them as BPA-free.

When mice were given bisphenol BPA or BPS in amounts that mimicked typical human levels, their heart function worsened, especially in females, within minutes of exposure.

These findings are concerning, as endocrine receptors and metabolic pathways are similar in mice and humans, said Pyle.

"This study raises concerns about the safety of BPS as a replacement for BPA."

It's particularly worrisome for people with coronary heart disease, high blood pressure, diabetes or obesity, because the effects of BPS could increase the chance of a heart attack or make a heart attack more severe, he added.

 

"If the heart is in a precarious position, when you add a stressor you can make it worse."

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Chemical Informatics-Open Access