Endocarditis: inflammation of the inner layer of the heart

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Endocarditis is an inflammation of the inner layer of the heart, the endocardium. It usually involves the heart valves. Other structures that may be involved include the interventricular septum, the chordae tendineae, the mural endocardium, or the surfaces of intracardiac devices. Endocarditis is characterized by lesions, known as vegetations, which is a mass of platelets, fibrin, microcolonies of microorganisms, and scant inflammatory cells In the subacute form of infective endocarditis, the vegetation may also include a center of granulomatous tissue, which may fibrose or calcify.

The simplest classification is based on cause: either infective or non-infective, depending on whether a microorganism is the source of the inflammation or not.

Regardless, the diagnosis of endocarditis is based on clinical features, investigations such as an echocardiogram, and blood cultures demonstrating the presence of endocarditis-causing microorganisms.

Signs and symptoms:                          

 fever, chills, sweating, malaise, weakness, anorexia, weight loss, splenomegaly, flu-like feeling, cardiac murmur, heart failure, petechia (red spots on the skin), Osler's nodes (subcutaneous nodules found on hands and feet), Janeway lesions (nodular lesions on palms and soles), and Roth's spots (retinal hemorrhages).

Our esteemed journal is looking forward for the upcoming issue. We are glad for the upcoming year issue release as all the authors are invited to submit their recent scientific work through manuscripts in the mode of Research/Case Reports/Case Studies/Reviews/Short Review/ Short Communications/Commentaries/Short

Our Journal welcomes submissions of manuscripts on the topics covering Atherosclerosis, Heart Attack, Ischemic Stroke, Cardiac ischemia, Plaque Attacks, Heart failure, Arrhythmia, Bradycardia, Tachycardia, Heart Valve problems, Angina, heart failure, etc. In the quality perspective, the journal is determined to maintain an exceptionally high standard in both facts and ethics. Accuracy and authenticity in the scientific reports of present journal are conserved above all nominal needs of the time.

A standard editorial manager system is utilized for manuscript submission, review, editorial processing and tracking which can be securely accessed by the authors, reviewers and editors for monitoring and tracking the article processing. Manuscripts can be uploaded online at Editorial Tracking System or as an email attachment to cmt@emedsci.com

Best Regards,
Samuel G,
Editorial Manager,
Journal of Cardiovascular Medicine and Therapy