Genetic Aspects of Gene Regulation

Image The current explosion of GWAS (Genome-Wide Association Study), driven in part by falling genotyping costs, has revealed some causal variants and others that have failed to replicate. In some cases, the observed linkage of associated SNPs to coding genes suggests that the associated variant might alter risk by regulating gene expression. cis-linked noncoding sequences often contain consensus binding sites for transcription factors, and recently, a causal variant for colorectal cancer was shown to be a cis-eQTL for SMAD7 expression, suggesting that other associated variants might alter diseas... Read More

“Genetic Engineering and Gene Therapy ”

Image On behalf of the Journal of Genomics & Gene Study, as Editor-in-Chief, it is my distinct honor and privilege to inform you that, it’s been ten long years we have started the Journal, now we are celebrating the 10th Anniversary and it is my great pleasure and honor to welcome you to the Journal of Genomics & Gene Study. Journal of Genomics & Gene Study aims to disseminate knowledge and promote discussion through the publication of peer-reviewe... Read More